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A prospective comparative study of mini‑PCNL using Swiss LithoClast® Trilogy or Thulium Fiber Laser with suction

Abhijit Patil, Rohan Sharma, Darshit Shah, Ankit Gupta1, Abhishek Singh, Arvind Ganpule, Ravindra Sabnis, Mahesh Desai, Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, India “A prospective comparative study of mini-PCNL using Trilogy®  or Thulium Fiber Laser with suction.” World Journal of Urology, 10.1007/s00345-021-03881-5. 28 Nov. 2021.

This prospective study aimed to evaluate and compare the efficiency of Swiss LithoClast® Trilogy and Thulium Fiber Laser in Mini-PCNL.

Case report: the end of “cutting for stone”? Using the Swiss LithoClast® Trilogy for cystolitholapaxy on a 4 cm bladder stone per urethra.

Sninsky B. C. et al. Urology Case Reports vol. 26 (2019) 100964.


The gold standard for managing extremely large or multiple bladder stones is still open cystolithotomy. In general, open surgical procedures are associated with more frequent complications than endoscopic ones. A traditional approach may be very challenging, especially in individuals with specific anatomical or physiological restrictions such as contractures or poor wound healing. Another aspect that has to be taken into account when treating patients with comorbidities is the type of energy used to fragment stones. When using a holmium laser, fragmentation and removing large bladder calculi may require a considerable amount of procedural time and the need for prolonged general anesthesia. Dual-energy lithotripters, on the other hand, present a better efficiency profile. Therefore, Swiss LithoClast® Trilogy - a single-probe device that combines electromagnetic impactor with ultrasonic energy and suction may serve as the best treatment solution in complex cases. 

Stone clearance times with mini-percutaneous nephrolithotomy: Comparison of a 1.5 mm ballistic/ultrasonic mini-probe vs. laser.

Timm B., et al. Canadian Urological Association Journal vol. 15,1 (2021): E17-E21.

Mini-percutaneous nephrolithotomy (Mini-PCNL) is a minimally invasive endoscopic procedure that requires a specific technique, as it utilizes relatively small instruments within restricted diameter access (to even 5 French or smaller). Treating renal calculi through the narrow working lumen of mini-nephroscopes represents the major challenge when conducting mini-PCNL.

Evaluation of intrarenal pressure stability at different lithotripter suction settings in a porcine kidney model

Strittmatter, F., Nagele, U., Schachtner, J. et al. Evaluation of intrarenal pressure stability at different lithotripter suction settings in a porcine kidney model. World J Urol (2021).


Intrarenal pressure levels with different suction levels were evaluated for Storz® Nephroscopes MIP-M and MIP-L in combination with Swiss LithoClast® Trilogy probes in an ex vivo porcine kidney model. 

Intracorporeal Lithotripsy Stone Retrieval for PCNL

Chosen by the experts: Swiss LithoClast®️ Trilogy - fast, easy and safe stone management!

Principal investigator: Amy E. Krambeck, Indiana University, Indianapolis, USA

The main goal of this multi-center, prospective, randomized trial, conducted by Dr. Krambeck and her team, was to evaluate the efficiency of two combination lithotripters for performing standard percutaneous nephrolithotomy (PCNL): Swiss LithoClast® Trilogy and Olympus® ShockPulse SE

Swiss LithoClast Trilogy: A European Multicenter Prospective Study

Multicenter single arm study to evaluate safety and effectiveness of Lithoclast Trilogy in a larger number of patients. 

Ten European clinical centers participate in this prospective, non-randomized trial. 
Oliver Wiseman (Principal investigator), Florin Tanse, Kasra Saeb-Parsy, Nabil Atassi, Renate Endriss, Laurian Dragos, Guido Kamphuis, Daniel Pèrez Fentes, Mudhar Hassan, Marianne Brehmer, Osther Palle, Helene Jung, Ben Turney, William Finch, Neil Burgess, Stuart Irving, Evangelos Liatsikos, Thomas Knoll, and Victor Cauni

EMS Lithoclast Trilogy: an effective single-probe dual-energy lithotripter for mini and standard PCNL

Sabnis R. B. et al. World Journal of Urology vol. 38,4 (2020): 1043-1050. 

Providing fast, easy, and safe percutaneous nephrolithotomy (PCNL) appears to be one of the most challenging issues in modern urology. In order to break the stones more effectively, a combination of different energy sources is needed. Swiss LithoClast® Trilogy is an all-in-one-probe, dual-energy lithotripter that combines electromagnetic impactor and ultrasonic vibration with suction capability. This study describes the initial clinical use of Swiss Lithoclast® Trilogy in patients who underwent Mini or Standard PCNL for stone evacuation.