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Eine prospektive vergleichende Studie zur Mini-PCNL mit Swiss LithoClast® Trilogy oder Thulium-Faserlaser mit Absaugung

Abhijit Patil, Rohan Sharma, Darshit Shah, Ankit Gupta1, Abhishek Singh, Arvind Ganpule, Ravindra Sabnis, Mahesh Desai, Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, India “A prospective comparative study of mini-PCNL using Trilogy®  or Thulium Fiber Laser with suction.” World Journal of Urology, 10.1007/s00345-021-03881-5. 28 Nov. 2021.

Ziel dieser prospektiven Studie war es, die Effizienz von Swiss LithoClast® Trilogy und Thulium-Faserlaser bei der Mini-PCNL zu bewerten und zu vergleichen.

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Initial Clinical Experience with Swiss LithoClast® Trilogy during Percutaneous Nephrolithotomy

Nottingham C. U. et al. Journal of Endourology, vol. 34,2 (2020): 151-155.

Study background 

Percutaneous nephrolithotomy (PCNL) is a gold standard treatment in patients with renal stones >20 mm in diameter. Several in vitro and laboratory model studies provided robust evidence on Swiss LithoClast® Trilogy efficiency. This modern, single-probe device delivers both ultrasonic energy and electromagnetic ballistic impact with a simultaneous suction capability.

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Stone clearance times with mini-percutaneous nephrolithotomy: Comparison of a 1.5 mm ballistic/ultrasonic mini-probe vs. laser.

Timm B., et al. Canadian Urological Association Journal vol. 15,1 (2021): E17-E21.

Mini-percutaneous nephrolithotomy (Mini-PCNL) is a minimally invasive endoscopic procedure that requires a specific technique, as it utilizes relatively small instruments within restricted diameter access (to even 5 French or smaller). Treating renal calculi through the narrow working lumen of mini-nephroscopes represents the major challenge when conducting mini-PCNL.

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Evaluation of intrarenal pressure stability at different lithotripter suction settings in a porcine kidney model

Strittmatter, F., Nagele, U., Schachtner, J. et al. Evaluation of intrarenal pressure stability at different lithotripter suction settings in a porcine kidney model. World J Urol (2021). https://doi.org/10.1007/s00345-021-03679-5

 

Intrarenal pressure levels with different suction levels were evaluated for Storz® Nephroscopes MIP-M and MIP-L in combination with Swiss LithoClast® Trilogy probes in an ex vivo porcine kidney model. 

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Comparative evaluation between one ultrasonic and two single-probe dual energy lithotripters: in vitro and in vivo experiment in a porcine model

M.Lattarulo et. al

Swiss LithoClast®️ Trilogy has been designed to provide powerful fragmentation and more efficient stone removal for shorter PCNL procedural time. Scientific research proves this effectiveness, in comparison to other, existing lithotripters, as well as in actual OR cases.
In a new study, Lattarulo et al. tested the Swiss LithoClast Trilogy in vitro and in vivo in porcine model, and concluded that the device is twice as fast on both soft and hard stones as compared with best competitors.

 

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Swiss LithoClast Trilogy: A European Multicenter Prospective Study

Multicenter single arm study to evaluate safety and effectiveness of Lithoclast Trilogy in a larger number of patients. 

Ten European clinical centers participate in this prospective, non-randomized trial. 
Oliver Wiseman (Principal investigator), Florin Tanse, Kasra Saeb-Parsy, Nabil Atassi, Renate Endriss, Laurian Dragos, Guido Kamphuis, Daniel Pèrez Fentes, Mudhar Hassan, Marianne Brehmer, Osther Palle, Helene Jung, Ben Turney, William Finch, Neil Burgess, Stuart Irving, Evangelos Liatsikos, Thomas Knoll, and Victor Cauni

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EMS Lithoclast Trilogy: an effective single-probe dual-energy lithotripter for mini and standard PCNL

Sabnis R. B. et al. World Journal of Urology vol. 38,4 (2020): 1043-1050. 

Providing fast, easy, and safe percutaneous nephrolithotomy (PCNL) appears to be one of the most challenging issues in modern urology. In order to break the stones more effectively, a combination of different energy sources is needed. Swiss LithoClast® Trilogy is an all-in-one-probe, dual-energy lithotripter that combines electromagnetic impactor and ultrasonic vibration with suction capability. This study describes the initial clinical use of Swiss Lithoclast® Trilogy in patients who underwent Mini or Standard PCNL for stone evacuation.

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